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What Are The Hazards of Lead To Human Health?

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What Are The Hazards of Lead To Human Health?

Update Time:2023/8/18
Lead has no physiological function on the human body, but can produce a variety of adverse effects. Lead has toxic effects on all systems and organs of the body. The main accumulation of hematopoietic, nervous, digestive, kidney system; In addition to the reproductive system and children's growth and development have a certain toxic effect.
(1) The effect of lead on the hematopoietic system: the effect of lead on the hematopoietic system is mainly due to the inhibition of porphyrin metabolism, which affects the synthesis of hemoglobin and causes anemia. The anemia caused by lead toxicity is not only due to the reduction of hemoglobin synthesis, but also due to the rupture of erythrocyte membrane caused by lead, leading to hemolysis. The hemolysis effect is obvious in acute lead poisoning, and the hemolysis effect is not important in chronic lead poisoning, which mainly affects the metabolism of hematoporphyrin.

(2) The effect of lead on the nervous system: The most studied is the effect of lead on the nervous system. Lead is an extremely sensitive poison to the human nervous system. Lead poisoning encephalopathy may occur in severe cases. Occupational lead encephalopathy is now rare. This situation is more common in non-occupational poisoning, acute and chronic can occur, such as children picking up lead paint painted wall skin or chewing toys coated with lead paint; Long-term consumption of beverages contaminated with lead can also occur in adults. Lead can also cause toxic peripheral neuropathy, mainly involving motor function, and the clinical manifestations are mainly extensor weakness, especially in the most used muscles. Often joint pain, with distal limb glove, sock like sensory disturbance. Severe patients have "lead paralysis" or "wrist droop".

(3) The effect of lead on the digestive system: lead poisoning can cause abnormal secretion and motor function of the digestive system. There are often loss of appetite, metallic taste in the mouth, bloating, constipation, nausea, dull pain in different parts of the abdomen, etc. In moderate and severe patients, sudden onset of abdominal colic (lead colic). Acute lead poisoning, lead can directly damage liver cells, and can cause small hepatic artery spasm to cause ischemia, acute lead poisoning liver disease; The liver damage caused by occupational chronic lead poisoning was not significant.

(4) The impact of lead on the kidney: lead can cause renal tubular dysfunction or even damage, early kidney damage may be recovered after treatment, but later may lead to renal insufficiency.

(5) Others: Studies have reported that lead also has an effect on cardiovascular, can cause hypertension; It can also affect the reproductive system, resulting in female infertility, abortion and teratogenesis, etc., and can also cause a decrease in male sperm motility and an increase in malformed sperm.

Lead test swabs can help us test the content of lead in everyday products to prevent from being exposed to large amounts of lead leading to lead poisoning. In daily life, the tableware, furniture, toys and so on that we use may contain lead, especially in newly bought products. Therefore, lead reagents are a good tool for our daily detection of lead content.